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Data was analysed by repeated measures one-way ANOVA or multiple t-tests (Prism) using a Holm-dks post-hoc analysis multiple comparison correction
in the context of a balanced triple agonist, its classical effect on hepatic glucose production is offset by the simultaneous GLP-1R/GIPR insulinotropic action, while the metabolic effects that peptide designers actually want from GCGR are retained: increased energy expenditure via brown-adipose thermogenesis and skeletal-muscle oxidation, adipose lipolysis with free-fatty-acid release for beta-oxidation, and hepatic fatty-acid oxidation that clears triglyceride from the liver 27
This does not mean treatment failed
Debe rotar sistemticamente los sitios de inyeccin con cada dosis, manteniendo al menos 1 pulgada (2.5 cm) de distancia del sitio anterior para prevenir cambios en el tejido que afecten la absorcin
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