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People want to get off blood pressure medications, but they see when they stop at their blood pressure, then shoots up
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Observational studies in humans report lower circulating spexin levels in obesity and metabolic syndrome, supporting its role as an endogenous metabolic regulator rather than a stress-induced peptide ( More recent analyses suggest that spexins metabolic actions may be dissociable from its nociceptive or affective effects through receptor subtype selectivity and dosing strategies ( 4.3 Meteorin-like protein (METRNL) and exercise-induced endocrinology Meteorin-like protein (METRNL) occupies a distinct conceptual niche within metabolic peptide biology
For someone weighing 100kg, this means you could expect to lose around 22kg with Mounjaro and 17kg with Wegovy 2.4 mg when combined with comprehensive support, both above the clinically significant threshold of 10%
