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Seek urgent medical advice if you experience: Severe or persistent gastrointestinal symptoms: Whilst mild nausea is common with Wegovy, severe or persistent vomiting, severe abdominal pain (especially if radiating to the back), or signs of dehydration require immediate assessment, as these may indicate pancreatitis or other serious complications

Choi JH, Lee KA, Moon JH, Chon S, Kim DJ, Kim HJ, Kim NH, Seo JA, Kim MK, Lim JH, Song Y, Yang YS, Kim JH, Lee YB, Noh J, Hur KY, Park JS, Rhee SY, Kim HJ, Kim HM, Ko JH, Kim NH, Kim CH, Ahn J, Oh TJ, Kim SK, Kim J, Han E, Jin SM, Choi WS, Moon MK

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That broader mechanism is a big part of why so many researchers see it as a step beyond earlier single-pathway compounds