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Side Effects Common side effects Nausea Diarrhea Vomiting Abdominal pain Fatigue Serious but less common side effects Pancreatitis Gallbladder disease (gallstones, cholecystitis) Kidney problems (from dehydration due to GI side effects) Potential increased risk of thyroid C-cell tumors (based on animal studies) Warnings and Precautions Contraindicated in patients with personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2)
Clinically, accumulating evidence indicates that combinations of L-carnitine with vitamin E, silymarin, or simvastatin can improve liver function and selected metabolic indices (38, 54, 55)
Mechanical agitation Shaking a vial of reconstituted tirzepatide is one of the fastest ways to cause aggregation
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