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The mCRP isoform, unlike nCRP, has a stimulatory effect on platelets, facilitates thrombus growth through platelet stimulation, and is the more potent reagent, both increasing monocyte activation and ROS production, generated through myeloperoxidase-mediated respiratory burst and raft-associated reduced nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase during oxLDL-mediated foam cell formation (170, 197204)
10.1097/MPG.0000000000002948 J Pediatr Gastroenterol Nutr
Grzybowski at Northwestern University
It is in virtually every one of our cells and it regenerates other common antioxidants like vitamin C and E
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