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Leflunomide can inhibit different signalling pathways such as Janus kinase/signal transducers and activators of transcription (JAK/STAT), and NF-B, with a subsequent decrease in pro-inflammatory cytokines, including IL-2, TNF-, and interferon-gamma (IFN-)

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We recommend that vegetables be boiled, drained, and cooked as much as possible, and that they be accompanied by a source of calcium (such as yoghurt, cheese, milk)