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Glutathione is synthesized endogenously by the sequential action of glutamate-cysteine ligase and glutathione synthetase

It includes 15 amino acids and has initially been studied in gut healing, although recent studies have explored its potential to aid in tendon repair, ligament repair, joint pain, inflammatory processes, tissue healing, and overall recovery

Curcumin extracted from the roots of Curcuma longa has exhibited anticancer, anti-inflammatory, antioxidant, and hypoglycemic effects (94)

The HRH2 gene is also expressed in additional cells of the gastrointestinal tract, cells of the central nervous system, smooth muscle cells, endothelial cells, and cardiomyocytes