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Structural collagen changes, no
Because the escalation phase occupied a large share of the study window and the trial ended at 46 weeks, the weight-loss curves had not clearly plateaued at every dose, meaning the ceiling of effect for survodutide in obesity remained an open question at Phase 2
Wegovy and Zepbound are FDA approved for weight loss, and Wegovy additionally received approval from the agency to treat cardiovascular conditions in patients with overweight or obesity in March
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