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Ketone bodies can actually inhibit approximately 40 percent of basal GLP-1 secretion through the FFAR3 receptor

Safety Considerations Common Mild Side Effects Nausea and stomach discomfort Diarrhea Fishy smell in breath or sweat (rare) Who Should Consult a Doctor First Individuals with heart diseases People with kidney problems Those with hormonal disorders Pregnant and nursing women Research Consideration: TMAO Some studies raise concerns about high levels of L-Carnitine from supplements possibly leading to increased TMAO (trimethylamine-N-oxide) production, which has been associated with higher risk of heart diseases

Staying hydrated is especially important while taking GLP-1s

After your first injection, you will continue to take semaglutide GLP-1 once a week, ideally on the same day each week