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In murine models of acute liver failure, early-stage liver stem cells (LSCs) demonstrate superior hepatoprotective effects compared to mature hepatocytes
Cochrane Database Syst Rev 2014, Issue 3
Since then, several GLP-1 mono-agonists have been approved, along with tirzepatide, the first dual GLP-1 and glucose insulinotropic polypeptide (GIP) receptor agonist
This action leads to a reduction in intracellular GSH levels, resulting in increased oxidative stress, which induces apoptosis and cell cycle arrest
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