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No lethal dose (LD50) has ever been determined because it has proven impossible to kill an animal with DSIP at any dose a remarkable finding for any bioactive compound
Measurement: 1.0 mg equals 3 units, 1.5 mg equals 4.5 units, and 2.0 mg equals 6 units
The pharmaceutical formulation may contain more than 90% w/w water, such as 90-99% w/w water, such as 91-99% w/w water, such as 92-99% w/w water, such as 93-99% w/w water 99% w/w water, such as 94-99% w/w water
Niimura et al., The experimental value of zebrafish as an animal model for in vivo drug discovery has grown rapidly due to their ease of assessment, large clutch size, and ability to recapitulate human disease conditions (MacRae and Peterson, in vivo , demonstrating that otoprotective drug discovery in zebrafish translates to mammalian systems (Owens et al., 2011)
