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A landmark study published in the New England Journal of Medicine found that participants using Semaglutide lost an average of 12.4% of their body weight over 68 weeks , compared to 2.4% in the placebo group
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Similarly, in another meta-analysis including 47 RCT and more than 23 thousand patients, patients receiving different GLP1RAs had a mean difference in weight of -5 kg relative to placebo [10]
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