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Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer
If you and your doctor determine you need more of an individual vitamin or nutrient, supplementing is usually safe, provided you stick with the recommended amount and avoid very high doses, which could have negative health effects (that goes for anyone, not just people who are breastfeeding!)
Analytical purity does not establish biological activity, safety, or clinical effectiveness
We thank Christopher Koscher for his assistance with protein expression and purification and Florian Grebien for help with establishing the RPE-1 cell lines stably expressing p53 and p53 mutants
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