(Those in the placebo group lost only about 2.4 percent of their starting weight.) That is an incredible difference.Thanks to the new FDA approval, an even higher dose of semaglutide, 2.4 mg, will now be sold specifically for weight loss under the brand name Wegovy

When to speak to your GP Contact your GP or rheumatologist if you experience: A significant RA flare after starting Wegovy or changing dose Persistent nausea or vomiting that affects your ability to take oral RA medications consistently New or worsening joint symptoms that dont follow your usual flare pattern Dehydration symptoms (dark urine, reduced urine output, dizziness), particularly if you take methotrexate, which requires adequate hydration for kidney clearance Significant weight loss that might affect your RA medication dosing Stomach pain or GI symptoms that are worse than expected, especially if youre taking NSAIDs or corticosteroids alongside Wegovy Feelings of low mood, anxiety, or being overwhelmed by managing your condition Frequently asked questions Is Wegovy safe with rheumatoid arthritis
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It may also request more data, labeling changes, or manufacturing clarifications before making a decision