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The most commonly reported AE with tirzepatide were gastrointestinal, including nausea, diarrhoea and vomiting

These combined actions underscore their therapeutic potential for NAFLD (89, 90)

(112) confirmed that gut microbiota-derived phenyl sulfate is an important contributor to albuminuria in diabetic kidney disease, suggesting that uremic toxin production and absorption can be reduced through modulation of gut microbiota metabolism