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The development of next-generation sequencing-based approaches to quantify senescence gene signatures in liquid biopsy samples is further expanding biomarker options, with several companies pursuing companion diagnostic programs in parallel with their senolytic drug development
Closed or near-closed epiphyses being a goal of approved use
The FDA has raised concerns about certain bodybuilding and performance-enhancement products, including products linked to liver injury, heart attack, stroke, hormone disruption, sexual dysfunction, mood changes, and other serious reactions
R.TangphaoO.et al (1998c)
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