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Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis

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In clinical practice, although liver function tests along with physical or imaging exams have been widely utilized as non-invasive screening methods to identify and assess different liver diseases, it is still vital to explore novel approaches to early diagnosis of liver diseases due to the lack of specificity and limitations of low sensitivity (Thapa and Walia, 2007