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(2023) Pentadecanoic Acid (C15:0), an Essential Fatty Acid, Shares Clinically Relevant Cell-Based Activities with Leading Longevity-Enhancing Compounds Venn-Watson, Stephanie, Jensen, Eric D (2025) Aging-Associated Amyloid- Plaques and Neuroinflammation in Bottlenose Dolphins (Tursiops truncatus) and Novel Cognitive Health-Supporting Roles of Pentadecanoic Acid (C15:0) Robinson, Miranda K
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York B, Reineke EL, Sagen JV, Nikolai BC, Zhou S, Louet JF, Chopra AR, Chen X, Reed G, Noebels J, Adesina AM, Yu H, Wong LJ, Tsimelzon A, Hilsenbeck S, Stevens RD, Wenner BR, Ilkayeva O, Xu J, Newgard CB, OMalley BW
In addition to the PFOS-induced pERK1/2 that is involved in autophagy activation, we revealed the inhibition of pmTOR and pAKT in PFOS-mediated RTC autophagy, which is an effect that can be reversed through l-Carnitine pretreatment (Fig
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