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Description

Achievement: Learning disabilities Adaptive behavior: Poor impulse control, poor personal boundaries, poor anger management, stubbornness, intrusive behavior, too friendly with strangers, poor daily living skills, developmental delays Attention: Attention-deficit/hyperactivity disorder (ADHD), poor attention or concentration, distractible Cognition: Intellectual disability, confusion under pressure, poor abstract skills, difficulty distinguishing between fantasy and reality, slower cognitive processing Executive functioning: Poor judgment, information-processing disorder, poor at perceiving patterns, poor cause and effect reasoning, inconsistent at linking words to actions, poor generalization ability Language: Expressive or receptive language disorders, grasp parts but not whole concepts, lack understanding of metaphor, idioms, or sarcasm Memory: Poor short-term memory, inconsistent memory and knowledge base Motor skills: Poor handwriting, poor fine motor skills, poor gross motor skills, delayed motor skill development (e.g., riding a bicycle at an appropriate age) Sensory processing and soft neurological problems: sensory processing disorder, sensory defensiveness, undersensitivity to stimulation Social communication: Intrude into conversations, inability to read nonverbal or social cues, "chatty" but without substance Secondary disabilities [edit] The secondary disabilities of FAS are those that arise later in life, secondary to central nervous system damage

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Degradation occurs through two main pathways: proteasome-mediated degradation and autophagy-lysosomal pathway (ALP)-mediated protein clearance

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