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Current evidence-based practices for obesity management involve multi-modal approaches, including lifestyle modification, mechanical gastric restriction, modulation in the secretion of multiple gut hormones, alteration in the composition and secretion of bile acids, and alterations of the gut microbiome
There is real science suggesting biological activity, but the clinical evidence is weak and conflicting
That is a 73% reduction in saliva production
Investigational drugs do not yet have the same clinical pathway
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