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Compounded sterile preparations are categorized into three risk levels: low (simple preparations using commercial sterile products with minimal handling), medium (complex formulas requiring multiple compounding steps), and high (preparations made from non-sterile ingredients or exposed to unsterile environments)

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Topical GHK-Cu does not require cycling because systemic copper absorption from creams and serums is minimal

Oral/buccal protocols: Continuous daily use is the standard documented approach for oral and buccal routes.