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Oxidative stress and major depression
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Each rat was adapted for 2 min and the total immobility time in the following 4 min was recorded
346 In parallel, modulation of microbial metabolites offers therapeutic leverage: promoting beneficial compounds such as 3-IAA, which enhances ROS and chemosensitivity, or suppressing lactate-secreting strains such as Lactobacillus iners may reverse resistance-associated metabolic reprogramming
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