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Inhibition of CaM kinase by KN-93 reduced the response to glutamine by approximately 60%, but the effect was not specific to glutamine, as KN-93 similarly impaired the secretory responses to glucose and alanine (data not shown)

Controls were setup as 100% of the ROS levels

Yilmaz M, Muftuoglu M, DiNardo CD, Kadia TM, Konopleva MY, Borthakur G, Pemmaraju N, Short NJ, Valero YA, Maiti A, Masarova L, Montalban-Bravo G, Jurisprudencia C, Pike A, Loghavi S, Patel KP, Tang G, Matthews J, Kornblau SM, Jabbour E, Garcia-Manero G, Ravandi F, Andreeff M , and Daver N

Discussion The continued production of new hippocampal neurons throughout adulthood is a multistage process sensitive to the state of oxygenation 34,50,51,52