melanotic macule oral Labial macule. B). Increased numbers of me-lanocytes along Pigmented (Purple or Brown) Lesions

Vitamin C : Supports glutathione recycling (best at balanced doses) Vitamin D and E : Beneficial when properly dosed Selenium : Essential for glutathione production Zinc : Supports immune function but too much can interfere Curcumin (Turmeric) : Boosts glutathione but must be from a pure source NAC (N-Acetyl Cysteine) : A strong precursor to glutathione Be cautious with combining multiple antioxidant supplements without professional guidance

Compared to synthetic compounds, natural phytochemicals are known for their lower toxicity, fewer side effects, higher safety, and diverse chemical profiles (Kapinova et al., 2018)

Glutathione is a well-known supplement especially in Korea, to improve dull, uneven skin tone and to fade hyperpigmentation, dark spots and acne marks

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