Contact your GP if you experience severe or persistent abdominal pain, persistent vomiting preventing fluid intake, signs of dehydration, or symptoms significantly impairing your quality of life
and a discontinued oral GLP-1 programme (danuglipron) that was terminated in late 2023 due to gastrointestinal tolerability issues that prevented adequate dose escalation
Clinically, GLP-1s improve blood sugar control and drive significant weight loss, with some also reducing cardiovascular risks
The choice between different GLP-1RAs, including Ozempic, Wegovy, Rybelsus, Mounjaro, Zepbound, Trulicity, Saxenda, and Victoza, often depends on patient-specific factors like efficacy, dosing frequency preference, side effect profile, and tolerance to the medication