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Women should be aware of any preexisting health issues, potential medication interactions, and avoid excessive or extended use without medical supervision
Emerging evidence suggests GLP-1 receptor agonists are associated with increased gallstone risk, with clinical trials showing gallbladder disorders in approximately 2.6% of patients on semaglutide versus 1.2% on placebo
Lovshin JA, Drucker DJ
However, the chosen sample sizes are consistent with those used in previous studies and were considered sufficient to detect biologically meaningful effects
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