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In designing a study, a goal of ME/CFS researchers should be to determine if a significant result can actually inform disease mechanisms, or if it is simply a reportable difference between patients and controls
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Given that FOXO4 is a transcription factor, this nuclear translocation suggests increased transcriptional activity
Both frowning and squinting are often signs you need to wear darker, larger sunglasses (or you need a Rx change on your glasses)
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