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It functions as a cofactor for mitochondrial enzymes specifically pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase that are essential for converting glucose into cellular energy (ATP) [1][2]
Additional information DISCLOSURE/CONFLICT OF INTEREST Michael Berk declares that over the past three years, he has received compensation from Stanley Medical Research Foundation, MBF, NHMRC, Beyond Blue, Geelong Medical Research Foundation, Bristol Myers Squibb, Eli Lilly, Glaxo SmithKline, Organon, Norvatis, Mayne Pharma and Servier
Long-term safety, interaction, endocrine, metabolic, and population-specific data remain incomplete
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