In contrast, excessive Se intake or environmental exposure was associated with an increased risk for type 2 diabetes, neurodegenerative diseases (amyotrophic lateral sclerosis and Parkinsons disease), and increased risk and mortality from some malignancies (carcinoma of prostate, buccal cavity, pharynx, stomach, colon, rectum, lungs, kidney, and urinary bladder, melanoma, multiple myeloma, lymphoid neoplasms, etc.) (43, 49, 50)
Sousa, M
Taken together, these findings suggest that carnitine pool homeostasis is closely related to inflammatory and immune homeostasis, tumor development, and immune escape, providing new perspectives and potential targets for the treatment of inflammatory diseases and cancer
An animal model testing butterbur extract observed similar anti-inflammatory effects on asthmatic mice (Brattstrm 2010)