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Key results (Phase 3): In a 68-week Phase 3a trial published in The New England Journal of Medicine , cagrilintidesemaglutide (CagriSema) produced large mean weight loss (reported as ~22.7% at 68 weeks in the main efficacy analysis)
The trend reflects a fundamental shift in the types of molecules being developed
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While standard L-carnitine supplements exist, they have limited ability to cross the blood-brain barrier where much of the cognitive benefits occur
