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GIP (glucose-dependent insulinotropic polypeptide) is a second incretin hormone that has complementary effects on insulin secretion, fat metabolism, and controversially may partially counterbalance GLP-1s GI side effects
BPC-157 decreased TNF-, IL-6, and IL-1 levels in tissue samples
It can lead to fluid retention, which increases the workload on the heart
On each day of the 10-week treatment period, oral administration was performed in the morning after an overnight fast of 10 h (water was allowed until 2 h before dosing) followed by 2-h post-dose fasting where subjects were not allowed to take any other oral concomitant medications
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