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According to the Cleveland Clinic, it is usually seen in people who do not get enough vitamin B12 from their diet or when their digestive tract does not absorb enough

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doi:10.2147/CCID.S128339

Here, we show the necessity of adenosine A2A receptor (A2AR) signaling and the GSH/GPX4 axis in orchestrating metabolic fitness and survival of functionally competent CD8 + T cells