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Increased reliance on fatty acid oxidation (FAO) alters mitochondrial electron flux and redox cofactor dynamics, influencing both anaboliccatabolic balance and oxidative buffering capacity
The dual indication profile for diabetes and inflammation could lead to faster regulatory paths, since proof of effectiveness in one indication could help speed up approval processes for diseases that are similar
Results guide personalized dosing: someone with a specific GLP1R variant may need higher semaglutide doses, while another patient achieves optimal results at lower doses
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