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Multivariable linear regression models were used to explain variation in the estimated positive and negative measurement bias

[5] The SURMOUNT-4 trial showed similar patterns for tirzepatide: patients switched from the drug to placebo regained about 14% of body weight over the following year, effectively erasing most of their loss

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In contrast, the potency at human GLP-1R of the exendin-4 disulphide stabilised fusion Ab#2_DSB#1 was better than the glycosylated variant Ab#2_GLP1 W25N/V27S although reduced compared to the non-modified exendin-4 antibody fusion (5.3 nM and to 110 pM, respectively)