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Those uncertain about potential copper sensitivity might consider patch testing before beginning injectable use

Several groups are developing strategies to improve the bioavailability of PTL, without having detrimental effects on its pharmacokinetic properties.1915 PTL can be successfully sequestered into nanoscopic vectors which can achieve equivalent toxicity to unmodified PTL.1816 Nanoparticle PTL formulations can be used in vivo at 40-fold lower doses with 20-fold lower administration frequency than standard PTL.16 Some of these delivery systems are inexpensive and formulations are readily scalable.18 Consequently, they should facilitate the use of PTL at clinically relevant doses