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The NHS and NICE recommend PDE5 inhibitors (sildenafil, tadalafil, vardenafil, avanafil) as first-line treatment, alongside lifestyle modifications and management of underlying conditions
Yoo, S.J
Langan RC, Goodbred AJ
While angiogenesis in the adult brain is classically considered quiescent under physiological conditions, mounting evidence from pathological contextssuch as stroke, trauma, glioma, and multiple sclerosisdemonstrates that angiogenic reactivation can occur in response to stress or injury (Thomsen et al
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