glutathione deficiency and seizures Intranasal Unifying mechanism behind the onset

Storage of peptides in solution Peptides in solution are less stable than their lyophilized counterparts

International Journal of Physiology, Pathophysiology and Pharmacology, 4 (2), 59-73

Amphetamines disrupt VMAT2 function and vesicular uptake through a combination of mechanisms: The Weak Base Effect (pH Gradient Collapse) : Amphetamines are lipophilic weak bases (pKa of 9.9) that can readily diffuse across both the plasma and vesicular membranes to accumulate inside synaptic vesicles (Wimalasena 2011)

In line with these observations, exposure of the SW480 colorectal cancer cell line to n -acetylcysteine yielded a synchronous upregulation of 3-MST and SQR expression and activity