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First, for sample normalization, we employed Quantile normalization, which adjusts the data to conform to a common distribution 81 , thereby minimizing technical variability
Later in 2023, a multisociety statement from gastroenterology and hepatology organizations, including the AGA, AASLD, ACG, ASGE, and NASPGHAN, advised against routine discontinuation and emphasized individualized risk assessment [9]
JAMA Psychiatry 71:423
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