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But advocating for weight-neutral alternatives when they exist is appropriate and important
Older age, prior heart failure (HF) and CV events, peripheral artery disease, and kidney complications can identify a subgroup of patients with T2D at high risk of mortality who are likely to achieve the greatest benefit from aggressive management of modifiable risk factors and newer glucose-lowering agents
Vaccines based on tumor-specific antigens are promising new therapeutic strategies, neoantigens can be presented to T cells by DCs system as a pool of short (8 to 11 amino acids) or long (15 or more residues) individual synthetic peptides or as unique long single molecule that concatenates the different neoantigens spaced by linker sequences (prepared as DNA, RNA or soluble protein)
A.ZemheriF.et al (2017)
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