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ADA Standards of Care 2025) recommend that patients with type 2 diabetes and atherosclerotic cardiovascular disease (ASCVD) (or high risk) should be on a GLP-1 RA with proven CV benefit (or an SGLT2 inhibitor) as part of their regimen, independent of A1c, because of the outcome benefits ( [9] ) ( [144] )
The absence of a control group precludes definitive conclusions on causality between GLP-1 receptor agonist therapy and observed outcomes, and residual confounding cannot be excluded In conclusion, arGLP-1 represent a valuable addition to the therapeutic arsenal for managing IWL or WR after BS
Unexplained weight loss beyond expected therapeutic effects, or inability to maintain adequate nutrition
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