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PubMed Central PMCID: PMCPMC3935991
[1] Ibuprofen belongs to the NSAID class and works by inhibiting cyclooxygenase (COX) enzymesspecifically COX-1 and COX-2which are responsible for producing prostaglandins
Other reported side effects include water retention, headaches, and joint stiffness
These enzymes are often upregulated in obesity and metabolic dysfunction
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