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Current perioperative decisions should be individualized according to drug type, dose-escalation phase, gastrointestinal symptoms, aspiration risk, and surgical urgency, rather than managed by a single universal rule ( Long-term use and discontinuation also need to be considered
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The peptides unique structural featurethe -glutamyl linkage between glutamic acid and cysteineprovides resistance to degradation by conventional peptidases
Tirzepatide produced greater average weight reduction in the head-to-head data discussed above
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