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The Lau monotherapy data cuts through that by showing the amylin analog producing double-digit weight loss entirely on its own, which is the cleanest argument that adding it to a triple agonist brings genuinely additive firepower rather than redundant signalling

Theres also a practical challenge: Health insurers dont typically cover obesity medications, says Scott Kahan, an obesity doctor and professor at Johns Hopkins Bloomberg School of Public Health and the George Washington University School of Medicine