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We need further research to understand the full potential of GLP-1 RAs and all the intricacies of their MOA for optimal clinical use
engineered a coaxial electrospun nanofibrous implant featuring spatially segregated therapeutic agents within a core shell architecture, wherein DOX was encapsulated in a hydrophilic PEO chitosan core while curcumin resided in a hydrophobic PCL chitosan shell, enabling independent tuning of release kinetics for synergistic combination chemotherapy through a single implantable patch
We chose to focus on SLC7A11 as playing a critical role in intracellular GSH levels, targeting SLC7A11 with erastin
doi:10.1016/S0304-4165(99)00123-3
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