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This enhanced stability allows more sustained receptor engagement in research settings
Check fasting glucose daily Check pre-meal and 2-hour post-meal glucose at least once daily Record all hypoglycemia events (glucose below 70 mg/dL) If fasting glucose drops below 80 mg/dL on 2+ consecutive days, reduce basal insulin by another 10% If post-meal glucose is consistently below 120 mg/dL, reduce bolus insulin by another 10 to 20% Step 4: Semaglutide dose escalation adjustments (every 4 weeks)
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