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The researchers noted that while drug-induced hypersensitivity reactions, including generalized pruritus and rash, have been documented, this presentation represented a delayed hypersensitivity reaction "characterized by well-defined, recurrent patches at discrete sites, driven by localized immune responses involving drug-specific cytotoxic T cells retained in the skin." Following discontinuation of semaglutide, the patient showed complete resolution of active lesions at 1-month follow-up, with residual postinflammatory hyperpigmentation
It mimics the natural hormone GLP1, which increases insulin secretion, decreases glucagon release, slows gastric emptying, and helps reduce appetite
What People Usually Notice The changes are gradual, which is why they are often ignored at first
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