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As crucial regulators of local immune responses and tissue repair, macrophages in diabetic wounds show dysregulated switching from M1 to M2, resulting in a poor regenerative environment, exacerbated tissue damage, and delayed wound healing 63
Without adequate L-Carnitine levels, fat utilization efficiency may decrease
Insulin resistance causes excess sugar to be stored as fat, and poor lymphatic circulation results in toxin and fluid retention , exacerbating bloating and fat accumulation
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