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These adverse effects can persist for several days, and may result in dehydration, which if severe may lead to other serious health complications.3 Nausea is the most common adverse effect reported with GLP-1 agonists with up to 50 percent of patients affected
In colitis, multiple proinflammatory cytokines within the intestinal tissue abnormally activate STAT3, resulting in intestinal barrier dysfunction, hyperactivation of innate immunity, and enhanced Th17-mediated immune responses, all of which contribute to chronic intestinal inflammation (Chen X
(2010) 298:R143543
These data come from a defined clinical population and have not been established as outcomes for the general public
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