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Over-the-counter anti-diarrheal medications such as loperamide (Imodium) or bismuth subsalicylate (Pepto-Bismol) can provide symptomatic relief during the adjustment period
GLP-1 receptor agonists predominantly target non-MC4R-dependent neural pathways in mice 19 , and there is evidence from a small clinical study with liraglutide 20 that they may be effective in people with MC4R deficiency
UK readers should see our peptide legality article for the local picture
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