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Spermidine was able to inhibit HAT activity in aging yeast, inhibit oxidative stress and necrosis, and trigger deacetylation of histone H3 (Eisenberg et al., 2009)
Apheresis can also help to remove microvascular blood clotting and has been shown to reduce autoantibodies in ME/CFS, but high costs limit its use (253)
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Yes, B12 injections are generally considered safe for most people, but its always a good idea to consult your doctor before starting, especially if you have any underlying health conditions
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